Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 10/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRK3 | P35626 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912707 | 0.95 | ADRB2 (0.48) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL10913832 | 0.87 | KMT2A (0.41) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10912083 | 0.83 | ADRB2 (0.45) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL10911968 | 0.82 | MEN1 (0.44) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10716763 | 0.81 | ABCB1 (0.41) | ADRB2ADRB1ADRB3TSHRSLC6A4 | |
| SCHEMBL10909793 | 0.81 | KMT2A (0.42) | ADRB2ADRB1ADRB3TSHRMEN1 | |
| SCHEMBL10913737 | 0.79 | ALDH1A1 (0.37) | TSHRMEN1ALOX15KMT2ALMNA | |
| Dimethylamine SCHEMBL10909871 | 0.79 | PDE10A (0.41) | HTR1ATSHRMEN1ALOX15KMT2A | |
| SCHEMBL10909846 | 0.79 | RAB9A (0.36) | TSHRMEN1ALOX15KMT2ALMNA | |
| SCHEMBL10911853 | 0.78 | RAB9A (0.38) | TSHRMEN1ALOX15KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |