Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11378463 | 0.85 | TACR1 (0.44) | TACR1OPRM1SLC6A4KMT2AMEN1 | |
| SCHEMBL11404600 | 0.85 | ALDH1A1 (0.49) | TACR1OPRM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11498170 | 0.84 | TACR1 (0.44) | TACR1OPRM1SLC6A4KMT2AMEN1 | |
| SCHEMBL10891234 | 0.80 | ALDH1A1 (0.62) | TACR1OPRM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL28514344 | 0.78 | ALDH1A1 (0.46) | TACR1OPRM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL7181893 | 0.78 | ALDH1A1 (0.60) | TACR1OPRM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10912937 | 0.78 | MAPT (0.49) | OPRM1KMT2AMEN1SMN1; SMN2NPC1 | |
| SCHEMBL11499971 | 0.76 | TACR1 (0.39) | TACR1OPRM1SLC6A4KMT2AMEN1 | |
| SCHEMBL10912458 | 0.76 | HSD17B10 (0.44) | TACR1OPRM1KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL11559949 | 0.75 | TACR1 (0.40) | TACR1OPRM1SLC6A4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027940-B2 | PROCESS FOR PREPARING URETHANES | BAYER AG (DE) | 1986-12-30 | — | — | EP | disclosed |
| EP-0027940-B1 | PROCESS FOR PREPARING URETHANES | BAYER AG (DE) | 1983-09-14 | — | — | EP | disclosed |
| EP-0027940-A1 | Process for preparing urethanes | BAYER AG (DE) | 1981-05-06 | — | — | EP | disclosed |