Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 4/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11498170 | 0.96 | TACR1 (0.44) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| SCHEMBL10911997 | 0.85 | TACR1 (0.53) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| SCHEMBL11571115 | 0.84 | TACR1 (0.45) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| Eclanamine SCHEMBL29388487 | 0.83 | OPRK1 (0.41) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| Eclanamine SCHEMBL11446626 | 0.83 | OPRK1 (0.41) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| Eclanamine SCHEMBL2109152 | 0.83 | OPRK1 (0.41) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| SCHEMBL11331105 | 0.80 | SIGMAR1 (0.40) | OPRM1ALDH1A1KMT2ASIGMAR1OPRK1 | |
| SCHEMBL11499971 | 0.80 | TACR1 (0.39) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| Eclanamine SCHEMBL29368460 | 0.77 | SLC6A4 (0.40) | TACR1OPRM1SLC6A4ALDH1A1KMT2A | |
| Eclanamine SCHEMBL124915 | 0.77 | SLC6A4 (0.40) | TACR1OPRM1SLC6A4ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |
| US-4159339-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4156014-A | N-(2-aminocycloheptyl)alkanoylanilides and in the treatment of depression | THE UPJOHN COMPANY (US) | 1979-05-22 | — | — | US | disclosed |