Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11559949 | 0.97 | TACR1 (0.40) | TACR1OPRM1L3MBTL1MEN1KMT2A | |
| SCHEMBL11378463 | 0.80 | TACR1 (0.44) | TACR1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL10911997 | 0.76 | TACR1 (0.53) | TACR1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL11498170 | 0.76 | TACR1 (0.44) | TACR1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL11549690 | 0.72 | OPRD1 (0.42) | OPRM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6492800 | 0.71 | LMNA (0.50) | KMT2AALDH1A1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL11561433 | 0.70 | TP53 (0.37) | MEN1KMT2AALDH1A1ATMGAA | |
| SCHEMBL11404600 | 0.70 | ALDH1A1 (0.49) | TACR1OPRM1MEN1KMT2AALDH1A1 | |
| SCHEMBL11454751 | 0.69 | OPRD1 (0.43) | OPRM1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11550476 | 0.68 | RAB9A (0.39) | OPRM1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4199589-A | N-(2-Aminocycloheptyl)acylanilides and methods to treat depression | SZMUSZKOVICZ JACOB (US) | 1980-04-22 | — | — | US | disclosed |
| US-4172898-A | N-(2-aminocycloheptyl)acylanilides | THE UPJOHN COMPANY (US) | 1979-10-30 | — | — | US | disclosed |