Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7526936 | 0.79 | CDK1 (0.35) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL842439 | 0.69 | ADORA2A (0.40) | — | |
| SCHEMBL11007131 | 0.68 | — | — | |
| SCHEMBL3158626 | 0.67 | CHUK (0.36) | MAPT | |
| SCHEMBL9208924 | 0.64 | — | — | |
| SCHEMBL497198 | 0.64 | KMT2A (0.36) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL5376352 | 0.61 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL19633362 | 0.60 | CDK1 (0.37) | ALDH1A1 | |
| SCHEMBL12726686 | 0.60 | CSNK2A2 (0.33) | KDM4EALDH1A1GAAMAPTPKM | |
| SCHEMBL14347071 | 0.58 | YTHDC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | disclosed |
| US-4536571-A | SEFL-DETOXIFYING ANTICARCINOGENIC AGENT | STOCKEL RICHARD F (US) | 1985-08-20 | — | — | US | disclosed |