Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.76 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.76 |
| ▸ | DRD3 | P35462 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | MAPT | P10636 | 7/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.75 |
| ▸ | MEN1 | O00255 | 5/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.56 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912735 | 1.00 | DRD2 (0.76) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10817030 | 0.91 | PTGS2 (0.82) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10817022 | 0.91 | PTGS2 (0.82) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10586452 | 0.90 | DRD2 (0.70) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10585024 | 0.89 | DRD2 (0.71) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10585030 | 0.89 | DRD2 (0.71) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10795884 | 0.89 | PTGS2 (0.78) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| SCHEMBL10795876 | 0.89 | PTGS2 (0.78) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| Cefprozil Anhydrous, (E)- SCHEMBL2901170 | 0.86 | PTGS2 (1.00) | DRD2PTGS2DRD3ALDH1A1MAPT | |
| Cefprozil Anhydrous, (E)- SCHEMBL5191958 | 0.86 | PTGS2 (1.00) | DRD2PTGS2DRD3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4520022-A | BACTERIAL INFECTION IN MAMMALS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | claimed |
| US-4591641-A | ORAL ANTIBIOTICS; GRAM NEGATIVE AND GRAM POSITIVE BACTERIA ACTIVITY | BRISTOL-MYERS COMPANY (US) | 1986-05-27 | — | — | US | disclosed |
| US-4520022-A | BACTERIAL INFECTION IN MAMMALS | BRISTOL-MYERS COMPANY (US) | 1985-05-28 | — | — | US | disclosed |