Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.30 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13341567 | 0.81 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL10912632 | 0.81 | POLB (0.33) | BCHEACHE | |
| SCHEMBL10913186 | 0.81 | PTK2 (0.34) | BCHEACHE | |
| SCHEMBL1225207 | 0.79 | AGBL2 (0.33) | AGBL2 | |
| SCHEMBL11174630 | 0.69 | — | — | |
| SCHEMBL11167289 | 0.64 | ALDH1A1 (0.39) | AGBL2 | |
| SCHEMBL13341568 | 0.62 | MAPT (0.33) | — | |
| SCHEMBL22298683 | 0.60 | MAP4K4 (0.38) | — | |
| SCHEMBL428478 | 0.59 | NPC1 (0.49) | GRM5 | |
| SCHEMBL10328696 | 0.59 | CYP4F2 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0074820-B1 | SUBSTITUTED PYRIMID-2-ONES, THE SALTS THEREOF, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NYEGAARD & CO. A/S (NO) | 1986-08-27 | — | — | EP | disclosed |
| US-4478839-A | CELL ANTIGROWTH AGENTS | NYEGAARD & CO. A/S (NO) | 1984-10-23 | — | — | US | disclosed |
| EP-0074820-A1 | Substituted pyrimid-2-ones, the salts thereof, processes for their preparation and pharmaceutical compositions containing them | NYEGAARD & CO. A/S (NO) | 1983-03-23 | — | — | EP | disclosed |