Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13341567 | 0.82 | AGBL2 (0.32) | AGBL2 | |
| SCHEMBL10912828 | 0.79 | SCN4A (0.32) | AGBL2 | |
| SCHEMBL11167289 | 0.72 | ALDH1A1 (0.39) | AGBL2KDM4E | |
| SCHEMBL11174630 | 0.68 | — | — | |
| SCHEMBL309283 | 0.64 | KDM4E (0.43) | KDM4E | |
| SCHEMBL13341568 | 0.61 | MAPT (0.33) | KDM4E | |
| SCHEMBL2326296 | 0.60 | PTGS1 (0.41) | AGBL2HCAR2KDM4E | |
| SCHEMBL10328694 | 0.60 | HCAR2 (0.41) | AGBL2HCAR2KDM4E | |
| SCHEMBL31456905 | 0.56 | HTT (0.42) | — | |
| SCHEMBL110129 | 0.55 | P4HTM (0.59) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102548979-B | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives | DOW AGROSCIENCES LLC | 2015-05-13 | — | — | CN | disclosed |
| CN-102548979-B | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives | DOW AGROSCIENCES LLC | 2015-05-13 | — | — | CN | disclosed |
| EP-2462133-B1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2014-09-24 | — | — | EP | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| US-8318758-B2 | 5-fluoro-2-oxopyrimidine-1(2H)-carboxylate derivatives | DOW AGROSCIENCES, LLC (US) | 2012-11-27 | — | — | US | disclosed |
| CN-102548979-A | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives | DOW AGROSCIENCES LLC | 2012-07-04 | — | — | CN | disclosed |
| CN-102548979-A | 5-fluoro-2-oxopyrimidine- 1(2h)-carboxylate derivatives | DOW AGROSCIENCES LLC | 2012-07-04 | — | — | CN | disclosed |
| EP-2462133-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| EP-2462133-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | Dow AgroSciences LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| WO-2011017544-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| WO-2011017544-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2011-02-10 | — | — | WO | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | ADAMA MAKHTESHIM LTD. (IL) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034491-A1 | 5-FLUORO-2-OXOPYRIMIDINE- 1(2H)-CARBOXYLATE DERIVATIVES | DDT, PFAS, CASP2 | AGBL2 962/4885HCAR2 1351/4885KDM4E 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.