Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10912064 | 0.90 | PDK2 (0.45) | POLBRAB9APDK2L3MBTL1HPGD | |
| SCHEMBL10913841 | 0.89 | POLB (0.39) | POLBRAB9ARPS6KA2L3MBTL1HPGD | |
| SCHEMBL10909601 | 0.86 | CHRNB2 (0.46) | POLBRAB9AL3MBTL1HPGDNPSR1 | |
| SCHEMBL10911877 | 0.84 | MAPT (0.55) | POLBNPSR1KMT2AHTTMAPT | |
| SCHEMBL10914345 | 0.84 | POLB (0.44) | POLBRAB9APDK2L3MBTL1KMT2A | |
| SCHEMBL10912198 | 0.84 | KCNH2 (0.41) | POLBRAB9APDK2L3MBTL1HPGD | |
| SCHEMBL10912912 | 0.83 | KMT2A (0.45) | POLBRAB9ARPS6KA2L3MBTL1HPGD | |
| SCHEMBL10909950 | 0.83 | TERT (0.45) | POLBRAB9AHPGDNPSR1KMT2A | |
| SCHEMBL10913535 | 0.83 | POLB (0.41) | POLBRAB9AHPGDNPSR1KMT2A | |
| Nitric Acid SCHEMBL10909519 | 0.82 | POLB (0.44) | POLBRAB9APDK2HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171977-A1 | Phthalimide derivatives, compositions containing them and a process for preparing them | SANKYO COMPANY LIMITED (JP) | 1986-02-19 | — | — | EP | disclosed |