Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.42 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10913642 | 1.00 | S1PR1 (0.47) | S1PR1PPARGPPARAMAOBCA12 | |
| SCHEMBL11079334 | 0.86 | S1PR1 (0.46) | S1PR1MAOBCTBP2POLBHRH3 | |
| SCHEMBL11079338 | 0.86 | S1PR1 (0.46) | S1PR1MAOBCTBP2POLBHRH3 | |
| SCHEMBL10543888 | 0.85 | ALDH1A1 (0.50) | S1PR1PPARGPPARAMAOBLMNA | |
| SCHEMBL10543906 | 0.85 | ALDH1A1 (0.50) | S1PR1PPARGPPARAMAOBLMNA | |
| SCHEMBL10543899 | 0.85 | ALDH1A1 (0.50) | S1PR1PPARGPPARAMAOBLMNA | |
| SCHEMBL10831514 | 0.82 | KDM4E (0.46) | S1PR1PPARGPPARAMAOBCA12 | |
| SCHEMBL10831510 | 0.82 | KDM4E (0.46) | S1PR1PPARGPPARAMAOBCA12 | |
| SCHEMBL11325721 | 0.82 | S1PR1 (0.44) | S1PR1PPARGPPARAMAOBCA12 | |
| SCHEMBL16202052 | 0.78 | SMN1; SMN2 (0.47) | S1PR1PPARGPPARAMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4598147-A | THIAZOLE INTERMEDIATES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-01 | — | — | US | disclosed |
| US-4372952-A | Cephem compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-08 | — | — | US | disclosed |
| US-4284631-A | 7-Substituted cephem compounds and pharmaceutical antibacterial compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-08-18 | — | — | US | disclosed |
| EP-0007633-A2 | Cephem compounds, processes for their preparation and pharmaceutical compositions containing them | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-02-06 | — | — | EP | disclosed |