Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 2/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079334 | 1.00 | S1PR1 (0.46) | S1PR1MAOBL3MBTL1MAPTPOLB | |
| SCHEMBL10543888 | 0.87 | ALDH1A1 (0.50) | S1PR1MAOBL3MBTL1NPC1RAB9A | |
| SCHEMBL10543899 | 0.87 | ALDH1A1 (0.50) | S1PR1MAOBL3MBTL1NPC1RAB9A | |
| SCHEMBL10543906 | 0.87 | ALDH1A1 (0.50) | S1PR1MAOBL3MBTL1NPC1RAB9A | |
| SCHEMBL10913642 | 0.86 | S1PR1 (0.47) | S1PR1MAOBPOLBCTBP2HRH3 | |
| SCHEMBL10913635 | 0.86 | S1PR1 (0.47) | S1PR1MAOBPOLBCTBP2HRH3 | |
| SCHEMBL10910012 | 0.83 | GAA (0.43) | S1PR1MAOBL3MBTL1MAPTPOLB | |
| SCHEMBL10910009 | 0.83 | GAA (0.43) | S1PR1MAOBL3MBTL1MAPTPOLB | |
| SCHEMBL2755830 | 0.77 | L3MBTL1 (0.50) | S1PR1MAOBL3MBTL1MAPTPOLB | |
| SCHEMBL5597204 | 0.75 | ALDH1A1 (0.47) | L3MBTL1CTBP2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0007633-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-04-18 | — | — | EP | disclosed |