SCHEMBL16202052

SCHEMBL16202052

CC(C)=NOCc1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 1/20 0.47
PTBP1 P26599 1/20 0.47
CA12 O43570 1/20 0.47
IDO1 P14902 2/20 0.47
AGXT P21549 2/20 0.47
S1PR1 P21453 1/20 0.45
MAOB P27338 6/20 0.45
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
POLB P06746 1/20 0.41
MAOA P21397 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
MAPT P10636 1/20 0.40
ALDH1A1 P00352 1/20 0.39
PKM P14618 1/20 0.39
APP P05067 1/20 0.39
TRPA1 O75762 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2755830 0.82 L3MBTL1 (0.50) SMN1; SMN2LMNAIDO1AGXTS1PR1
SCHEMBL15081032 0.82 L3MBTL1 (0.41) SMN1; SMN2LMNAPOLBNPC1RAB9A
SCHEMBL28545074 0.80 NPC1 (0.56) SMN1; SMN2LMNAIDO1MAOBPPARG
SCHEMBL10864019 0.80 IDO1 (0.52) CA12IDO1AGXTS1PR1MAOB
SCHEMBL25923625 0.80 L3MBTL1 (0.50) SMN1; SMN2IDO1AGXTMAOBPPARG
SCHEMBL25923630 0.79 MAOB (0.49) SMN1; SMN2CA12S1PR1MAOBPPARA
SCHEMBL678711 0.79 MAPT (0.57) SMN1; SMN2LMNAIDO1MAOBPPARG
SCHEMBL15504890 0.78 IDO1 (0.52) SMN1; SMN2IDO1AGXTS1PR1MAOB
SCHEMBL25923622 0.78 IDO1 (0.53) SMN1; SMN2IDO1AGXTMAOBMAOA
SCHEMBL10913635 0.78 S1PR1 (0.47) SMN1; SMN2LMNAPTBP1CA12IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-10-26 US disclosed
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-27 US disclosed
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2023-07-27 US disclosed
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2016-09-01 US disclosed
US-9271501-B2 Use of strobilurin type compounds for combating phytopathogenic fungi resistant to QO inhibitors BASF SE (DE) 2016-03-01 US disclosed
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors BASF SE (DE) 2014-10-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140323305-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB SMN1; SMN2 2724/4885LMNA 3613/4885PTBP1 2774/4885
US-20230337672-A1 METHOD OF CONTROLLING SOYBEAN RUST FUNGUS HAVING RESISTANCE TO QoI FUNGICIDE CYC1, SQOR, MT-CO1 SMN1; SMN2 4428/4885LMNA 2102/4885PTBP1 3711/4885
US-20160249615-A1 Use of Strobilurin Type Compounds for Combating Phytopathogenic Fungi Resistant to QO Inhibitors SQOR, COX5B, UQCRB SMN1; SMN2 2724/4885LMNA 3613/4885PTBP1 2774/4885
US-20230232827-A1 METHOD FOR CONTROLLING SOYBEAN RUST FUNGUS RESISTANT TO QoI FUNGICIDES CYC1, SQOR, MT-CO3 SMN1; SMN2 4452/4885LMNA 2445/4885PTBP1 3990/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.