Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 3/20 | 0.44 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10915056 | 0.90 | KDM4E (0.50) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9634951 | 0.88 | ALDH1A1 (0.51) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6776958 | 0.87 | ADRB2 (0.59) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL10501517 | 0.87 | ALDH1A1 (0.51) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10913555 | 0.87 | KDM4E (0.55) | ALDH1A1KDM4EHPGDHSD17B10TOP2A | |
| SCHEMBL10443823 | 0.86 | ALDH1A1 (0.56) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10914967 | 0.85 | ADRB2 (0.53) | KCNH2ADRB2TOP2ATOP2B | |
| SCHEMBL9677389 | 0.84 | KCNH2 (0.53) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10913622 | 0.81 | ALDH1A1 (0.49) | KCNH2ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL7817401 | 0.81 | ADRB2 (0.47) | KCNH2ALDH1A1POLBOPRM1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |