Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CLK2 | P49760 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694326 | 0.90 | ALDH1A1 (0.54) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL27691603 | 0.88 | ALDH1A1 (0.57) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7817401 | 0.84 | ADRB2 (0.47) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10915056 | 0.84 | KDM4E (0.50) | ALDH1A1POLBKDM4EHPGDHSD17B10 | |
| SCHEMBL312188 | 0.84 | ALDH1A1 (0.69) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL9636148 | 0.82 | KDM4E (0.53) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7824399 | 0.81 | KDM4E (0.70) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL10913645 | 0.81 | KCNH2 (0.46) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL7823514 | 0.80 | ALDH1A1 (0.56) | ALDH1A1POLBOPRM1CHRM2CHRM1 | |
| SCHEMBL10920186 | 0.80 | ALDH1A1 (0.58) | ALDH1A1POLBOPRM1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | claimed |
| EP-0205029-A2 | Quinolinecarboxylic acids with an antibacterial activity | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |