Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GRK6 | P43250 | 1/20 | 0.44 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10724090 | 0.90 | MAPT (0.49) | MAPTHPGDPOLBCTSBMEN1 | |
| SCHEMBL10915430 | 0.86 | ALDH1A1 (0.46) | MAPTMEN1KMT2AGRK6ALDH1A1 | |
| SCHEMBL10377541 | 0.81 | NPC1 (0.50) | MAPTPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL10377358 | 0.81 | NPC1 (0.50) | MAPTPOLBMEN1KMT2AL3MBTL1 | |
| SCHEMBL4491339 | 0.77 | ALDH1A1 (0.56) | MAPTHPGDPOLBMEN1KMT2A | |
| SCHEMBL10914093 | 0.77 | ALDH1A1 (0.46) | MAPTPOLBMEN1KMT2AALDH1A1 | |
| SCHEMBL6960011 | 0.76 | ALDH1A1 (0.54) | MAPTMEN1KMT2AGRK6ALDH1A1 | |
| SCHEMBL6960006 | 0.76 | ALDH1A1 (0.54) | MAPTMEN1KMT2AGRK6ALDH1A1 | |
| SCHEMBL10375543 | 0.75 | NPC1 (0.52) | MAPTALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL10377412 | 0.74 | ALDH1A1 (0.46) | MAPTHPGDMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202654-A2 | 5-Carboxy-1,4-dihydropyrimidine derivatives | E.R. Squibb & Sons, Inc. (US) | 1986-11-26 | — | — | EP | disclosed |