Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.67 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10911705 | 0.87 | ALDH1A1 (0.63) | ALDH1A1MAPK10KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10914663 | 0.86 | ALDH1A1 (0.62) | ALDH1A1MAPK10KDM4EKMT2AMEN1 | |
| SCHEMBL10914273 | 0.80 | ALDH1A1 (0.61) | ALDH1A1MAPK10KDM4EKMT2AMEN1 | |
| SCHEMBL10913488 | 0.79 | KMT2A (0.60) | ALDH1A1MAPK10KDM4ECYP2C19KMT2A | |
| SCHEMBL10911236 | 0.78 | KMT2A (0.59) | ALDH1A1MAPK10KDM4ECYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL10911309 | 0.78 | CHEK1 (0.58) | ALDH1A1MAPK10KDM4EKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL10914090 | 0.78 | KMT2A (0.58) | ALDH1A1MAPK10KDM4EKMT2AMEN1 | |
| SCHEMBL10914678 | 0.77 | ALDH1A1 (0.72) | ALDH1A1MAPK10KDM4EKMT2AMEN1 | |
| SCHEMBL5312292 | 0.77 | LMNA (0.67) | ALDH1A1KMT2AMEN1TSHRSMN1; SMN2 | |
| SCHEMBL10915546 | 0.76 | KDM4E (0.57) | ALDH1A1MAPK10KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4585774-A | Aniline derivatives and cardiotonic composition | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-04-29 | — | — | US | disclosed |
| EP-0064878-B1 | NOVEL ANILINE DERIVATIVES, PROCESS FOR PREPARING THE SAME AND CARDIOTONIC COMPOSITIONS CONTAINING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-07-24 | — | — | EP | disclosed |
| EP-0064878-A1 | Novel aniline derivatives, process for preparing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-11-17 | — | — | EP | disclosed |