Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | FPR2 | P25090 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | ARG1 | P05089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916148 | 0.82 | FPR2 (0.46) | FPR2ALDH1A1KMT2AOPRD1OPRK1 | |
| SCHEMBL10986597 | 0.82 | TNF (0.48) | TNF | |
| SCHEMBL31584352 | 0.80 | FPR2 (0.41) | FPR2POLBDUTTNF | |
| SCHEMBL31584367 | 0.80 | TNF (0.37) | FPR2ALDH1A1DUTKDM4ETNF | |
| SCHEMBL2633151 | 0.75 | KMT2A (0.50) | FPR2SMN1; SMN2ALDH1A1POLBKMT2A | |
| SCHEMBL4235144 | 0.72 | SMN1; SMN2 (0.37) | FPR2SMN1; SMN2ALDH1A1KMT2AOPRD1 | |
| SCHEMBL2627811 | 0.72 | SMN1; SMN2 (0.63) | FPR2SMN1; SMN2 | |
| SCHEMBL25395276 | 0.69 | CNR2 (0.37) | ALDH1A1KMT2AHDAC8DUTTNF | |
| SCHEMBL23745443 | 0.69 | FPR2 (0.39) | FPR2SMN1; SMN2ALDH1A1OPRD1OPRK1 | |
| SCHEMBL15335292 | 0.69 | ALPL (0.47) | FPR2SMN1; SMN2ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055562-B1 | CEPHALOSPORIN DERIVATIVES | ICI PHARMA (FR) | 1986-02-12 | — | — | EP | disclosed |
| US-4492692-A | BACTERICIDE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-01-08 | — | — | US | disclosed |
| EP-0055562-A2 | Cephalosporin derivatives | ICI PHARMA (FR) | 1982-07-07 | — | — | EP | disclosed |