Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 5/20 | 0.41 |
| ▸ | TNF | P01375 | 11/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31584367 | 0.85 | TNF (0.37) | FPR2TNFDUTCNR2 | |
| SCHEMBL10916000 | 0.80 | MAPK13 (0.37) | FPR2TNFPOLBDUT | |
| SCHEMBL10553435 | 0.74 | FPR2 (0.51) | FPR2POLBATR | |
| SCHEMBL21137544 | 0.73 | FGFR1 (0.38) | FPR2TNFDUT | |
| SCHEMBL31584536 | 0.73 | TNF (0.43) | TNFDUTCNR2 | |
| SCHEMBL31584986 | 0.73 | KDM4E (0.39) | TNF | |
| SCHEMBL2633151 | 0.72 | KMT2A (0.50) | FPR2POLB | |
| SCHEMBL4235144 | 0.72 | SMN1; SMN2 (0.37) | FPR2 | |
| SCHEMBL29068022 | 0.71 | GRM2 (0.43) | POLB | |
| SCHEMBL12636575 | 0.70 | FPR2 (0.46) | FPR2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106863-A1 | LACTAM DERIVATIVES FOR INHIBITING NLRP3 AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-05-22 | — | — | WO | disclosed |