Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9633842 | 0.79 | TNKS (0.52) | HRH2HRH1OPRM1ADORA3HTR2A | |
| SCHEMBL28015716 | 0.77 | CHRM3 (0.58) | CHRM3HRH2HRH1ALDH1A1KDM4E | |
| SCHEMBL28286998 | 0.68 | GAA (0.54) | CHRM3HRH2HRH1GAA | |
| SCHEMBL9292241 | 0.68 | CHRM3 (0.67) | CHRM3HRH2HRH1OPRM1PKM | |
| SCHEMBL11106836 | 0.68 | NPC1 (0.52) | ALDH1A1TSHRGAA | |
| SCHEMBL3864848 | 0.66 | CHRM3 (0.62) | CHRM3PKM | |
| SCHEMBL27629467 | 0.66 | SIGMAR1 (0.56) | HRH2HRH1OPRM1ADORA3HTR2A | |
| SCHEMBL28015708 | 0.66 | SLC6A4 (0.45) | CHRM3ALDH1A1KDM4ETSHRSIGMAR1 | |
| SCHEMBL28015740 | 0.66 | SLC6A4 (0.47) | HRH1ALDH1A1KDM4ETSHR | |
| SCHEMBL5546140 | 0.65 | GRIN2B (0.47) | HRH2HRH1ALDH1A1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0166509-A1 | Phenol derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-01-02 | — | — | EP | disclosed |