Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.58 |
| ▸ | HRH2 | P25021 | 2/20 | 0.50 |
| ▸ | HRH1 | P35367 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015725 | 0.86 | CHRM3 (0.46) | CHRM3KDM4EALDH1A1TSHRHTR7 | |
| SCHEMBL28015708 | 0.86 | SLC6A4 (0.45) | CHRM3KDM4EALDH1A1TSHRSIGMAR1 | |
| SCHEMBL28015740 | 0.83 | SLC6A4 (0.47) | HRH1KDM4EALDH1A1TSHR | |
| SCHEMBL27518463 | 0.82 | MGLL (0.53) | KDM4EALDH1A1TSHRGAA | |
| SCHEMBL28286998 | 0.80 | GAA (0.54) | CHRM3HRH2HRH1KCNH2GAA | |
| SCHEMBL28015720 | 0.80 | ALDH1A1 (0.47) | HRH1KDM4EALDH1A1TSHRGAA | |
| SCHEMBL10730867 | 0.79 | HRH2 (0.61) | HRH2HRH1KDM4EALDH1A1TSHR | |
| SCHEMBL3864848 | 0.78 | CHRM3 (0.62) | CHRM3PKMDRD3KCNH2 | |
| SCHEMBL27629467 | 0.78 | SIGMAR1 (0.56) | HRH2HRH1OPRM1ADORA3HTR2A | |
| SCHEMBL10916456 | 0.77 | CHRM3 (0.45) | CHRM3HRH2HRH1PKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |