SCHEMBL10916488

SCHEMBL10916488

CCOC(=O)c1c(-c2ncccc2C)n[nH]c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 3/20 0.43
PDE4D Q08499 1/20 0.41
SMO Q99835 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 1/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGDS O60760 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
POLB P06746 1/20 0.40
IDO1 P14902 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
BRD4 O60885 1/20 0.40
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10919890 0.90 TDP2 (0.43) TDP2PDE4DSMN1; SMN2NPC1RAB9A
SCHEMBL10919855 0.84 PDE4D (0.45) TDP2PDE4DSMN1; SMN2ALDH1A1HPGDS
SCHEMBL10919570 0.82 LMNA (0.47) PDE4DSMN1; SMN2NPC1RAB9ALMNA
SCHEMBL9749016 0.81 KMT2A (0.45) SMN1; SMN2NPC1RAB9ALMNAALDH1A1
SCHEMBL10514354 0.79 PDE4D (0.40) PDE4DSMN1; SMN2NPC1RAB9ALMNA
SCHEMBL10918426 0.78 GRM6 (0.42) TDP2PDE4DSMN1; SMN2NPC1RAB9A
SCHEMBL10920620 0.78 ALDH1A1 (0.49) PDE4DSMN1; SMN2LMNAALDH1A1HPGDS
SCHEMBL10919404 0.77 PDE4D (0.40) PDE4DSMN1; SMN2LMNAALDH1A1HPGDS
SCHEMBL10924140 0.76 PDE4D (0.43) PDE4DSMN1; SMN2NPC1RAB9ALMNA
SCHEMBL10923243 0.75 PDE4D (0.41) PDE4DNPC1ALDH1A1HPGDSPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0189069-A2 Pyrazolesulfonamide derivative, process for its production and herbicide containing it NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1986-07-30 EP disclosed