Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12410906 | 0.84 | GAA (0.52) | ALDH1A1L3MBTL1GAATDP1CYP1A2 | |
| Propane SCHEMBL10920259 | 0.78 | ALDH1A1 (0.47) | ALDH1A1TDP1KMT2ALMNAHTT | |
| Propane SCHEMBL10924092 | 0.77 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1GAATDP1KMT2A | |
| Propane SCHEMBL10851565 | 0.77 | KMT2A (0.39) | ALDH1A1CYP1A2CASP1KMT2ALMNA | |
| Propane SCHEMBL10924005 | 0.74 | HTT (0.36) | ALDH1A1CYP1A2CASP1KMT2ALMNA | |
| SCHEMBL10811543 | 0.74 | GAA (0.60) | ALDH1A1L3MBTL1GAATDP1CYP1A2 | |
| SCHEMBL12410776 | 0.72 | LMNA (0.52) | ALDH1A1L3MBTL1GAATDP1CYP1A2 | |
| Propane SCHEMBL10860075 | 0.72 | KMT2A (0.35) | ALDH1A1GAAKMT2ALMNAHTT | |
| Propane SCHEMBL10922828 | 0.71 | TDP1 (0.48) | ALDH1A1TDP1CYP1A2KMT2ALMNA | |
| Propane SCHEMBL10852960 | 0.71 | KMT2A (0.34) | ALDH1A1L3MBTL1KMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0114045-B1 | PYRIMIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1986-09-03 | — | — | EP | claimed |