Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278014 | 0.81 | MAPK1 (0.37) | MAPK1MAPTPOLBATMGRM2 | |
| SCHEMBL6827979 | 0.77 | MAPK1 (0.33) | MAPK1MAPTPOLBATM | |
| SCHEMBL6279767 | 0.69 | GRM2 (0.42) | MAPK1MAPTGRM2 | |
| Water SCHEMBL22636774 | 0.64 | POLB (0.52) | MAPK1POLBATMPKM | |
| SCHEMBL3282850 | 0.62 | GRM2 (0.50) | MAPK1MAPTPOLBATMGRM2 | |
| SCHEMBL3286257 | 0.62 | GRM2 (0.50) | MAPK1MAPTPOLBATMGRM2 | |
| SCHEMBL3676899 | 0.62 | PKM (0.56) | MAPK1POLBATMPKM | |
| SCHEMBL1305111 | 0.62 | MAPK1 (0.37) | MAPK1MAPTPOLBATMPKM | |
| SCHEMBL3278710 | 0.62 | PKM (0.56) | MAPK1POLBATMPKM | |
| SCHEMBL3280154 | 0.59 | POLB (0.37) | MAPK1MAPTPOLBATMPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202046-A1 | 7-Substituted bicyclic pyrazolidinones | ELI LILLY AND COMPANY (US) | 1986-11-20 | — | — | EP | disclosed |