SCHEMBL3278710

SCHEMBL3278710

On1nnc2cc(Cl)ccc21

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.56
POLB P06746 1/20 0.53
MAPK1 P28482 1/20 0.53
ATM Q13315 1/20 0.53
CHEK1 O14757 1/20 0.50
LIMK1 P53667 1/20 0.50
MAPK14 Q16539 1/20 0.50
CLK4 Q9HAZ1 1/20 0.50
KCNMA1 Q12791 2/20 0.48
CTNNB1 P35222 9/20 0.45
TCF7L2 Q9NQB0 1/20 0.44
KEAP1 Q14145 2/20 0.41
KMO O15229 1/20 0.41
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3676899 1.00 PKM (0.56) PKMPOLBMAPK1ATMCHEK1
SCHEMBL5702771 0.84 POLB (0.47) PKMPOLBMAPK1ATMCHEK1
SCHEMBL29373587 0.84 POLB (0.53) PKMPOLBMAPK1ATMCHEK1
SCHEMBL83509 0.84 POLB (0.53) PKMPOLBMAPK1ATMCHEK1
Water SCHEMBL2477026 0.82 POLB (0.52) PKMPOLBMAPK1ATMCHEK1
Hydrochloric Acid SCHEMBL30439745 0.82 POLB (0.52) PKMPOLBMAPK1ATMCHEK1
Water SCHEMBL22636774 0.82 POLB (0.52) PKMPOLBMAPK1ATMCHEK1
SCHEMBL11264259 0.79 CHEK1 (0.53) CHEK1LIMK1MAPK14CLK4KCNMA1
Pyrrole SCHEMBL25279873 0.78 KMO (0.50) POLBMAPK1ATMKCNMA1KMO
SCHEMBL16863946 0.78 PKM (0.58) PKMPOLBMAPK1ATMCTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9475916-B2 Process for curing surface-coating compositions ALLNEX AUSTRIA GMBH (AT) 2016-10-25 US claimed
US-20140356540-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2014-12-04 US claimed
WO-2006131828-A1 A PROCESS FOR THE PREPARATION OF PERINDOPRIL AUROBINDO PHARMA LIMITED (IN) 2006-12-14 WO claimed
EP-1092762-B1 Storage stable compositions comprising mediators, peroxide compounds and pH stabilizers, and their use in enzymatic bleaching systems BAYER CHEMICALS AG (DE) 2004-12-08 EP claimed
US-6380142-B1 FOR USE IN ENZYMATIC TWO-COMPONENT BLEACHING SYSTEMS BAYER AKTIENGESELLSCHAFT (DE) 2002-04-30 US claimed
EP-1092762-A1 Storage stable compositions comprising mediators, peroxide compounds and pH stabilizers, and their use in enzymatic bleaching systems Bayer Aktiengesellschaft (DE) 2001-04-18 EP claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed
CN-113671068-B Method for analyzing environmental pollutant targeted exposure group in blood plasma and application thereof 暨南大学 2023-01-24 CN disclosed
EP-0745154-A1 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM Lignozym GmbH (DE) 1996-12-04 EP disclosed
WO-1996018770-A2 MULTICOMPONENT SYSTEM FOR MODIFYING, DECOMPOSING OR BLEACHING LIGNIN, LIGNIN-CONTAINING MATERIALS OR SIMILAR SUBSTANCES AND METHOD OF USING THIS SYSTEM LIGNOZYM GMBH (DE) 1996-06-20 WO disclosed
EP-0717143-A1 Multicomponents system for modifying decomposing or bleaching of lignin or materials containing it or similar components and the way to use it Lignozym GmbH (DE) 1996-06-19 EP disclosed
EP-0047491-A2 New cephem compounds and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1982-03-17 EP disclosed
EP-0002774-B1 PROCESS FOR ACYLATING 7AMINOCEPHEM DERIVATIVES HOECHST AKTIENGESELLSCHAFT (DE) 1981-09-23 EP disclosed
EP-0002774-A1 Process for acylating 7aminocephem derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1979-07-11 EP disclosed
US-4052373-A O-AMINOESTER FUJI PHOTO FILM CO., LTD. (JA) 1977-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB PKM 1813/4885POLB 310/4885MAPK1 235/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.