Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 9/20 | 0.45 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3278710 | 1.00 | PKM (0.56) | PKMPOLBMAPK1ATMCHEK1 | |
| SCHEMBL5702771 | 0.84 | POLB (0.47) | PKMPOLBMAPK1ATMCHEK1 | |
| SCHEMBL29373587 | 0.84 | POLB (0.53) | PKMPOLBMAPK1ATMCHEK1 | |
| SCHEMBL83509 | 0.84 | POLB (0.53) | PKMPOLBMAPK1ATMCHEK1 | |
| Water SCHEMBL2477026 | 0.82 | POLB (0.52) | PKMPOLBMAPK1ATMCHEK1 | |
| Hydrochloric Acid SCHEMBL30439745 | 0.82 | POLB (0.52) | PKMPOLBMAPK1ATMCHEK1 | |
| Water SCHEMBL22636774 | 0.82 | POLB (0.52) | PKMPOLBMAPK1ATMCHEK1 | |
| SCHEMBL11264259 | 0.79 | CHEK1 (0.53) | CHEK1LIMK1MAPK14CLK4KCNMA1 | |
| Pyrrole SCHEMBL25279873 | 0.78 | KMO (0.50) | POLBMAPK1ATMKCNMA1KMO | |
| SCHEMBL16863946 | 0.78 | PKM (0.58) | PKMPOLBMAPK1ATMCTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524898-B2 | Proton acceptor iminium/carbocation-type coupling agents | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2013-09-03 | — | — | US | disclosed |
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2010-06-10 | — | — | US | disclosed |
| EP-2170822-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | Luxembourg Bio Technologies Ltd. (IL) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008139481-A2 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | LUXEMBOURG BIO TECHNOLOGIES LTD. (IL) | 2008-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144588-A1 | PROTON ACCEPTOR IMINIUM/CARBOCATION-TYPE COUPLING AGENTS | PHAX, GIPR, IAPP | PKM 792/4885POLB 156/4885MAPK1 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.