Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 9/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10917805 | 0.99 | NPC1 (0.49) | NPC1RECQLABCB1HTR1AALDH1A1 | |
| Hydrochloric Acid SCHEMBL10919861 | 0.89 | MAPT (0.58) | HTR1AALDH1A1KMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL10919243 | 0.89 | ABCB1 (0.48) | ABCB1HTR1AALDH1A1KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL10921685 | 0.87 | ABCB1 (0.43) | ABCB1HTR1AALDH1A1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL10919658 | 0.87 | ALDH1A1 (0.48) | ABCB1ALDH1A1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL10923347 | 0.85 | ABCB1 (0.42) | ABCB1HTR1AALDH1A1MAPTHTT | |
| Hydrochloric Acid SCHEMBL10921255 | 0.85 | PDE3B (0.52) | ABCB1HTR1AALDH1A1LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL11179632 | 0.85 | LMNA (0.42) | ABCB1HTR1AALDH1A1MAPTHTT | |
| SCHEMBL10918979 | 0.83 | ALDH1A1 (0.52) | NPC1ALDH1A1KMT2AMAPTLMNA | |
| SCHEMBL10917978 | 0.83 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064704-B1 | 4-AMINOMETHYL-5-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-04-16 | — | — | EP | claimed |
| US-4381393-A | 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1983-04-26 | — | — | US | claimed |
| EP-0064704-A1 | 4-Aminomethyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | claimed |