Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 2/20 | 0.61 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | P4HB | P07237 | 1/20 | 0.51 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920181 | 1.00 | MAOB (0.70) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL11461960 | 0.85 | MAOB (0.68) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL11461958 | 0.83 | MAOB (0.66) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL9586253 | 0.83 | ALDH1A1 (0.70) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL11461959 | 0.83 | MAOB (0.66) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL977524 | 0.83 | MAOB (1.00) | MAOBALDH1A1CES2LMNAP4HB | |
| Acetic Acid SCHEMBL10942212 | 0.83 | MAOB (0.65) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL977523 | 0.83 | MAOB (1.00) | MAOBALDH1A1CES2LMNAP4HB | |
| SCHEMBL29742914 | 0.81 | CES2 (0.67) | MAOBALDH1A1CES2SRD5A2LMNA | |
| SCHEMBL1031954 | 0.81 | CES2 (0.67) | MAOBALDH1A1CES2SRD5A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064385-B1 | 2,6-DIARYL-PYRIDINECARBOXYLIC ACIDS AND THEIR THERAPEUTIC UTILITY | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | disclosed |
| US-4377586-A | Diuretic 2,6-diaryl-4-pyridine carboxylic acids | THE UPJOHN COMPANY (US) | 1983-03-22 | — | — | US | disclosed |
| US-4127656-A | Method of inhibiting lipogensis with 3-(benzoyl)oxiranecarboxamides | SHELL OIL COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
| US-4091221-A | LIPOGENESIS INHIBITORS | SHELL OIL COMPANY (US) | 1978-05-23 | — | — | US | disclosed |
| US-3953463-A | 2-Aryl-6-trifluoromethyl-4-pyridyl-carbinolamine antimalarials | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-04-27 | — | — | US | disclosed |
| US-3940404-A | PLASMODIAL INFECTIONS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-02-24 | — | — | US | disclosed |