Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.66 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | HBB | P68871 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | CCND2 | P30279 | 1/20 | 0.39 |
| ▸ | CCND3 | P30281 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31290216 | 1.00 | DHFR (0.66) | DHFRTP53HBBSMN1; SMN2APEX1 | |
| Teroxirone SCHEMBL4472568 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL2097375 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL28584318 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL2097151 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL4932 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL4461477 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL4470513 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| Teroxirone SCHEMBL4452999 | 0.80 | TP53 (1.00) | DHFRTP53HBBSMN1; SMN2MAPT | |
| SCHEMBL15164280 | 0.79 | TP53 (0.64) | DHFRTP53HBBSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0033503-B1 | MEDICAMENTS WITH CYTOSTATIC ACTIVITY AND USE OF CYCLIC COMPOUNDS, IN WHICH THE HETEROCYCLIC N-RING ATOMS ARE SUBSTITUTED BY SEVERAL GLYCIDYL GROUPS, IN PHARMACEUTICAL COMPOSITIONS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0033503-A2 | Medicaments with cytostatic activity and use of cyclic compounds, in which the heterocyclic N-ring atoms are substituted by several glycidyl groups, in pharmaceutical compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-08-12 | — | — | EP | disclosed |
| EP-0033503-A2 | Medicaments with cytostatic activity and use of cyclic compounds, in which the heterocyclic N-ring atoms are substituted by several glycidyl groups, in pharmaceutical compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1981-08-12 | — | — | EP | disclosed |
| US-3985825-A | EPOXIDE RESIN MOLDING MATERIALS FROM POLYESTER-DICARBOXYLIC ACIDS | CIBA-GEIGY CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |