Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11046315 | 0.98 | MAPT (0.50) | MAPTTDP1CA12CA1CA2 | |
| SCHEMBL6852879 | 0.91 | CA1 (0.52) | MAPTTDP1CA12CA1CA2 | |
| SCHEMBL1505827 | 0.89 | TDP1 (0.61) | MAPTTDP1CA12CA1CA2 | |
| SCHEMBL4496440 | 0.88 | APEX1 (0.51) | MAPTTDP1KDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL2202243 | 0.87 | TDP1 (0.59) | MAPTTDP1CA12CA1CA2 | |
| SCHEMBL6240686 | 0.82 | CA1 (0.44) | MAPTTDP1CA12CA1CA2 | |
| Methyl 2,3,4-Trimethoxybenzoate SCHEMBL1434191 | 0.82 | ALDH1A1 (0.57) | MAPTTDP1KDM4EALDH1A1POLB | |
| SCHEMBL31172701 | 0.80 | KDM4E (0.46) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL11046314 | 0.80 | CA1 (0.43) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL419245 | 0.79 | TDP1 (0.56) | MAPTTDP1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1179960-C | Indole derivatives and their use in the treatment of osteoporosis and other uses | ʷ��˿�������ȳ�ķ�ɷݹ�˾ | 2004-12-15 | — | — | CN | disclosed |
| EP-0799827-B1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN SEIYAKU KK (JP) | 2004-05-12 | — | — | EP | disclosed |
| CN-1370159-A | Indole derivatives and their use for treatment of osteoporosis amongst other applications | SMITHKLINE BEECHAM SPA (IT) | 2002-09-18 | — | — | CN | disclosed |
| US-5786486-A | ANTIMICROBIAL, ANTITUMOR AGENTS | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| EP-0799827-A1 | ACRYLAMIDE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |