Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD2 | P25440 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10918631 | 0.80 | LMNA (0.39) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL4139773 | 0.77 | ALDH1A1 (0.39) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL2139894 | 0.75 | LMNA (0.42) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL10920553 | 0.74 | LMNA (0.37) | LMNAMAPTHTTTYMPALDH1A1 | |
| SCHEMBL576274 | 0.73 | LMNA (0.33) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL575834 | 0.73 | LMNA (0.33) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL10463617 | 0.73 | LMNA (0.40) | LMNAMAPTHTTTYMPALDH1A1 | |
| SCHEMBL25275054 | 0.72 | BACE1 (0.39) | LMNAMAPTHTTCYP1A2CYP2C9 | |
| SCHEMBL5765527 | 0.72 | LMNA (0.36) | LMNAMAPTHTTCYP1A2CYP3A4 | |
| SCHEMBL9548115 | 0.71 | LMNA (0.39) | LMNAMAPTHTTTYMPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049977-B1 | INSECTICIDAL (1,1'-BIPHENYL)-3-YLMETHYL ESTERS, THEIR PRODUCTION AND USE AND COMPOSITIONS CONTAINING THEM | FMC Corporation (US) | 1986-02-26 | — | — | EP | disclosed |
| US-4536591-A | Insecticidal [1,1'-biphenyl]-3-ylmethyl esters | FMC CORPORATION (US) | 1985-08-20 | — | — | US | disclosed |
| US-4402973-A | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters | FMC CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |