Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TYMP | P19971 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920553 | 0.88 | LMNA (0.37) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL10463617 | 0.88 | LMNA (0.40) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL7713106 | 0.82 | LMNA (0.48) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL247368 | 0.82 | LMNA (0.48) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL6402127 | 0.79 | LMNA (0.46) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL7704707 | 0.79 | LMNA (0.46) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL7711087 | 0.79 | ALDH1A1 (0.50) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL31305580 | 0.77 | LMNA (0.43) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL17747946 | 0.76 | LMNA (0.48) | LMNAMAPTHTTALDH1A1TYMP | |
| SCHEMBL14182621 | 0.76 | LMNA (0.48) | LMNAMAPTHTTALDH1A1TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5194293-A | — | — | None | — | — | JP | disclosed |
| JP-H05194293-A | PREPARATION OF TERTIARY TRI-AND TETRAFLUOROPHENYLBENZYL ALCOHOLS | MERCK PATENT GMBH | 1993-08-03 | — | — | JP | disclosed |