Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | RARB | P10826 | 8/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217323 | 0.94 | RAB9A (0.52) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8039966 | 0.89 | RARB (0.49) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8052200 | 0.88 | RAB9A (0.43) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8773176 | 0.85 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8773157 | 0.85 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8982894 | 0.85 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8983021 | 0.85 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL8773119 | 0.85 | MAPT (0.70) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10501599 | 0.84 | MAPT (0.74) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL10500496 | 0.84 | MAPT (0.74) | MAPTRAB9ASMN1; SMN2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4533488-A | COMPONENT OF LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1985-08-06 | — | — | US | claimed |
| JP-59039876-A | — | — | None | — | — | JP | disclosed |
| EP-0104011-B1 | PYRIMIDINE DERIVATIVES | Chisso Corporation (JP) | 1986-04-23 | — | — | EP | disclosed |
| US-4533488-A | COMPONENT OF LIQUID CRYSTAL COMPOSITIONS | CHISSO CORPORATION (JP) | 1985-08-06 | — | — | US | disclosed |
| EP-0104011-A1 | Pyrimidine derivatives | Chisso Corporation (JP) | 1984-03-28 | — | — | EP | disclosed |
| JP-S5939876-A | PYRIMIDINE DERIVATIVE | CHISSO CORP | 1984-03-05 | — | — | JP | disclosed |