Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | CCR5 | P51681 | 1/20 | 0.55 |
| ▸ | CCR8 | P51685 | 1/20 | 0.55 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | BCR | P11274 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.49 |
| ▸ | PHGDH | O43175 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19072768 | 0.93 | CCR1 (0.52) | CCR1CCR5CCR8ABL1BCR | |
| SCHEMBL2161283 | 0.86 | ABL1 (0.55) | CCR1CCR5CCR8ABL1BCR | |
| SCHEMBL13692259 | 0.85 | ABL1 (0.58) | CCR1CCR5CCR8ABL1BCR | |
| SCHEMBL19258816 | 0.83 | NOS3 (0.52) | ABL1BCRSYKKDM1ANOS3 | |
| SCHEMBL16545818 | 0.81 | CCR1 (0.65) | CCR1CCR5CCR8ABL1BCR | |
| SCHEMBL13692256 | 0.81 | NOS3 (0.42) | ABL1BCRKDM1ANOS3NOS2 | |
| SCHEMBL19248528 | 0.80 | SYK (0.41) | CCR1CCR5CCR8ABL1BCR | |
| SCHEMBL19072769 | 0.80 | TDP1 (0.43) | ABL1BCRKDM1ANOS3NOS2 | |
| SCHEMBL15495642 | 0.78 | ABL1 (0.52) | CCR1CCR5CCR8ABL1BCR | |
| SCHEMBL20224615 | 0.77 | CCR1 (0.53) | CCR1CCR5CCR8ABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | claimed |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | IONKIN ALEX SERGEY | 2009-02-26 | — | — | US | claimed |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-12-14 | — | — | US | claimed |
| EP-2016154-B1 | ELECTROLUMINESCENT BIS-CYCLOMETALLED IRIDIUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS | DU PONT (US) | 2012-06-13 | — | — | EP | disclosed |
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-8153794-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-04-10 | — | — | US | disclosed |
| US-7737277-B2 | Electroluminescent bis-cyclometalled iridium compounds and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2010-06-15 | — | — | US | disclosed |
| US-7595501-B2 | fluorinated 2-phenylpyridine compounds complexed with iridium; improved luminescence efficiency | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-29 | — | — | US | disclosed |
| US-7595501-B2 | fluorinated 2-phenylpyridine compounds complexed with iridium; improved luminescence efficiency | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090206326-A1 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WITH FLUORINATED PHENYLPRYIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | LG CHEM, LTD. (KR) | 2009-08-20 | — | — | US | disclosed |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | IONKIN ALEX SERGEY | 2009-02-26 | — | — | US | disclosed |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | IONKIN ALEX SERGEY | 2009-02-26 | — | — | US | disclosed |
| EP-2016154-A2 | ELECTROLUMINESCENT BIS-CYCLOMETALLED IRIDIUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-01-21 | — | — | EP | disclosed |
| US-7449601-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449601-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| US-7449601-B2 | Catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2008-11-11 | — | — | US | disclosed |
| WO-2007133523-A2 | ELECTROLUMINESCENT BIS-CYCLOMETALLED IRIDIUM COMPOUNDS AND DEVICES MADE WITH SUCH COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-11-22 | — | — | WO | disclosed |
| US-20070259205-A1 | Electroluminescent bis-cyclometalled iridium compounds and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2007-11-08 | — | — | US | disclosed |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090206326-A1 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WITH FLUORINATED PHENYLPRYIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | QDPR, DPYD, KCNQ5 | CCR1 3498/4885CCR5 2019/4885CCR8 3382/4885 |
| US-20090054650-A1 | Novel Catalysts Useful for Catalyzing the Coupling of Arylhalides with Arylboronic Acids | DDT, AHR, DDC | CCR1 3906/4885CCR5 3482/4885CCR8 4471/4885 |
| US-20060281923-A1 | Novel catalysts useful for catalyzing the coupling of arylhalides with arylboronic acids | DDT, AHR, DDC | CCR1 3906/4885CCR5 3482/4885CCR8 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.