Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6954552 | 0.78 | TBXAS1 (0.53) | KMT2ANPC1RAB9ACTNNB1WNT3A | |
| SCHEMBL31557727 | 0.73 | CES2 (0.62) | KMT2ACTNNB1WNT3ACES2LMNA | |
| SCHEMBL10922844 | 0.72 | MEN1 (0.48) | KDM4EALOX15HDAC1HDAC6HDAC8 | |
| SCHEMBL2096246 | 0.72 | CES2 (0.61) | KMT2ACTNNB1WNT3ACES2LMNA | |
| SCHEMBL9468405 | 0.72 | ALDH1A1 (0.61) | HDAC1KMT2ANPC1RAB9ACTNNB1 | |
| SCHEMBL25348845 | 0.72 | CES2 (0.61) | KMT2ACTNNB1WNT3ACES2LMNA | |
| SCHEMBL31557717 | 0.72 | CES2 (0.61) | KMT2ACTNNB1WNT3ACES2LMNA | |
| SCHEMBL744906 | 0.72 | CTNNB1 (0.62) | KMT2ARAB9ACTNNB1WNT3ACYP2C19 | |
| SCHEMBL4508253 | 0.72 | CES2 (0.61) | KMT2ACTNNB1WNT3ACES2LMNA | |
| SCHEMBL28415441 | 0.72 | CES2 (0.61) | KMT2ACTNNB1WNT3ACES2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0073999-B1 | PYRIDIN-4-ONE DERIVATIVES SUBSTITUTED BY A HETEROCYCLIC RING, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BAYER AG (DE) | 1986-01-15 | — | — | EP | disclosed |
| US-4451282-A | Herbicidally active novel hetero-substituted pyrid-4-one derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |
| EP-0073999-A2 | Pyridin-4-one derivatives substituted by a heterocyclic ring, process for their preparation and their use as herbicides | BAYER AG (DE) | 1983-03-16 | — | — | EP | disclosed |