Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | LGMN | Q99538 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15681572 | 0.86 | TERT (0.56) | MGAMHDAC3HDAC1HDAC2TERT | |
| SCHEMBL21835803 | 0.84 | CHEK1 (0.53) | MGAMHDAC3HDAC1HDAC2KDM4E | |
| SCHEMBL8727055 | 0.84 | HDAC3 (0.60) | MGAMHDAC3HDAC1HDAC2TERT | |
| Hydrochloric Acid SCHEMBL15534244 | 0.83 | HDAC3 (0.59) | MGAMHDAC3HDAC1HDAC2KCNH2 | |
| SCHEMBL17737093 | 0.80 | KDM4E (0.47) | MAPTTHRBLGMNKDM4EMEN1 | |
| SCHEMBL11014645 | 0.78 | MGAM (0.45) | MGAMHDAC3HDAC1HDAC2KCNH2 | |
| SCHEMBL27971212 | 0.77 | MGAM (0.53) | MGAMTERTEGLN1MAPTKDM4E | |
| SCHEMBL15666121 | 0.77 | CKS1B (0.48) | MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL10619057 | 0.76 | MAPT (0.40) | MGAMHDAC3HDAC1HDAC2MAPT | |
| SCHEMBL27970978 | 0.76 | MGAM (0.51) | MGAMTERTEGLN1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0090424-B1 | NEW QUINOLONE COMPOUNDS AND PREPARATION THEREOF | STERLING DRUG INC. (US) | 1986-05-28 | — | — | EP | disclosed |