Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 8/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
| ▸ | MGAM | O43451 | 1/20 | 0.49 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR5A | P47898 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15534244 | 0.99 | HDAC3 (0.59) | HDAC3HDAC1HDAC2KCNH2MGAM | |
| Hydrochloric Acid SCHEMBL15534450 | 0.87 | HDAC3 (0.60) | HDAC3HDAC1HDAC2KCNH2ABL1 | |
| SCHEMBL15681572 | 0.86 | TERT (0.56) | HDAC3HDAC1HDAC2KCNH2MGAM | |
| SCHEMBL10922894 | 0.84 | MGAM (0.49) | HDAC3HDAC1HDAC2KCNH2MGAM | |
| SCHEMBL21835803 | 0.84 | CHEK1 (0.53) | HDAC3HDAC1HDAC2MGAMABL1 | |
| SCHEMBL10618123 | 0.81 | HDAC3 (0.49) | HDAC3HDAC1HDAC2KCNH2ABL1 | |
| SCHEMBL15534500 | 0.81 | HDAC3 (0.50) | HDAC3HDAC1HDAC2KCNH2ABL1 | |
| SCHEMBL10866344 | 0.78 | HDAC3 (0.41) | HDAC3HDAC1HDAC2KCNH2MGAM | |
| SCHEMBL11014645 | 0.78 | MGAM (0.45) | HDAC3HDAC1HDAC2KCNH2MGAM | |
| SCHEMBL9837631 | 0.77 | HTR3E (0.49) | HDAC3HDAC1HDAC2KCNH2MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106863562-A | A kind of steam pressure kettle device steam-cured for air entrained concrete idiosome and its method of work | 徐州工程学院 | 2017-06-20 | — | — | CN | claimed |
| EP-0130119-B1 | (ACYLOXYALKOXY) CARBONYL DERIVATIVES AS BIOREVERSIBLE PRODRUG MOIETIES FOR PRIMARY AND SECONDARY AMINE FUNCTIONS IN DRUGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | MERCK & CO. INC. (US) | 1988-11-09 | — | — | EP | claimed |
| EP-0069385-B1 | USE OF EUCALYPTOL FOR ENHANCING SKIN PERMEATION OF BIOAFFECTING AGENTS | MERCK & CO. INC. (US) | 1987-10-14 | — | — | EP | claimed |
| EP-0036138-B1 | COMPOSITION OF MATTER FOR TOPICAL APPLICATION COMPRISING A BIO-AFFECTING AGENT AND N,N-DIETHYL-M-TOLUAMIDE | MERCK & CO. INC. (US) | 1985-08-28 | — | — | EP | claimed |
| CN-104721154-B | Norfloxacin glutamate freeze-dried powder injection pharmaceutical composition for injection | 山东北大高科华泰制药有限公司 | 2018-02-06 | — | — | CN | disclosed |
| CN-106863562-A | A kind of steam pressure kettle device steam-cured for air entrained concrete idiosome and its method of work | 徐州工程学院 | 2017-06-20 | — | — | CN | disclosed |
| CN-1048242-C | 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | NORTHERN CONTINENTAL CO LTD (JP) | 2000-01-12 | — | — | CN | disclosed |
| US-5777181-A | 2, 4, 5-trihalogeno- and 2, 3, 4, 5-tetrahalogenobenzene derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1998-07-07 | — | — | US | disclosed |
| CN-1117491-A | 5-amino-8-methyl-7-pyrrolidinylquinoline-3-carboxylic acid derivative | NORTHERN CONTINENTAL CO LTD (JP) | 1996-02-28 | — | — | CN | disclosed |
| EP-0130119-B1 | (ACYLOXYALKOXY) CARBONYL DERIVATIVES AS BIOREVERSIBLE PRODRUG MOIETIES FOR PRIMARY AND SECONDARY AMINE FUNCTIONS IN DRUGS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | MERCK & CO. INC. (US) | 1988-11-09 | — | — | EP | disclosed |
| EP-0069385-B1 | USE OF EUCALYPTOL FOR ENHANCING SKIN PERMEATION OF BIOAFFECTING AGENTS | MERCK & CO. INC. (US) | 1987-10-14 | — | — | EP | disclosed |
| EP-0036145-B1 | AN ORALLY ADMINISTERED DRUG FORM COMPRISING A POLAR BIOACTIVE AGENT AND AN ADJUVANT | INTERx RESEARCH CORPORATION (US) | 1985-05-29 | — | — | EP | disclosed |
| EP-0031561-B1 | A RECTALLY ADMINISTERED SUPPOSITORY COMPRISING A DRUG AND AN ADJUVANT | MERCK & CO. INC. (US) | 1985-04-10 | — | — | EP | disclosed |