Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15681572 | 0.80 | TERT (0.56) | MGAMHDAC3HDAC1HDAC2ABL1 | |
| SCHEMBL8727055 | 0.78 | HDAC3 (0.60) | MGAMHDAC3HDAC1HDAC2ABL1 | |
| SCHEMBL21835803 | 0.78 | CHEK1 (0.53) | MGAMHDAC3HDAC1HDAC2ABL1 | |
| SCHEMBL10922894 | 0.78 | MGAM (0.49) | MGAMHDAC3HDAC1HDAC2KCNH2 | |
| SCHEMBL10619332 | 0.77 | HPGDS (0.41) | MGAMHDAC3HDAC1HDAC2ABL1 | |
| Hydrochloric Acid SCHEMBL15534244 | 0.77 | HDAC3 (0.59) | MGAMHDAC3HDAC1HDAC2ABL1 | |
| SCHEMBL10866344 | 0.76 | HDAC3 (0.41) | MGAMHDAC3HDAC1HDAC2ABL1 | |
| SCHEMBL209690 | 0.76 | USP2 (0.61) | KHKNAMPTDPP4USP2 | |
| SCHEMBL10461264 | 0.75 | CHRNA7 (0.52) | KHKHTR2BHTR6HTR1ADRD2 | |
| SCHEMBL2413103 | 0.74 | POLB (0.54) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0131839-A1 | Quinoline antibacterial compounds | ABBOTT LABORATORIES (US) | 1985-01-23 | — | — | EP | disclosed |