Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Maleic Acid SCHEMBL10923024 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1GAAL3MBTL1TDP1 | |
| Fumaric Acid SCHEMBL10923030 | 0.89 | KDM4E (0.61) | KDM4EALDH1A1GAAL3MBTL1TDP1 | |
| SCHEMBL1760893 | 0.83 | L3MBTL1 (0.58) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL28462887 | 0.82 | KDM4E (0.58) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL10922618 | 0.80 | ADRB2 (0.51) | KDM4EALDH1A1ADRB2 | |
| SCHEMBL27865353 | 0.79 | KDM4E (0.62) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL13251247 | 0.79 | L3MBTL1 (0.57) | KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL8076614 | 0.78 | ADRB2 (0.53) | KDM4EALDH1A1ADRB2 | |
| SCHEMBL19271780 | 0.78 | DRD2 (0.60) | KDM4EALDH1A1L3MBTL1ADRB2 | |
| SCHEMBL171811 | 0.78 | L3MBTL1 (0.68) | KDM4EALDH1A1GAAL3MBTL1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066987-B1 | N-(ARYLOXYALKYL)-N'-(AMINO-ALKYL) UREAS | A.H. ROBINS COMPANY, INCORPORATED (US) | 1986-08-27 | — | — | EP | disclosed |
| US-4558155-A | N-(Aryloxyalkyl)-N'-(aminoalkyl)thioureas | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-12-10 | — | — | US | disclosed |
| US-4500529-A | ANTIARRHYTHMIA AGENT | A. H. ROBINS COMPANY, INCORPORATED (US) | 1985-02-19 | — | — | US | disclosed |
| EP-0066987-A2 | N-(aryloxyalkyl)-N'-(amino-alkyl) ureas | A.H. ROBINS COMPANY, INCORPORATED (US) | 1982-12-15 | — | — | EP | disclosed |