Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928226 | 0.87 | CYP2D6 (0.41) | CYP19A1MAPTKDM4EESR2TBXAS1 | |
| SCHEMBL10928352 | 0.85 | RAB9A (0.37) | CYP19A1MAPTKDM4EESR2TBXAS1 | |
| SCHEMBL10928337 | 0.85 | TBXAS1 (0.36) | CYP19A1MAPTKDM4EESR2TBXAS1 | |
| SCHEMBL10928215 | 0.84 | RAB9A (0.54) | CYP19A1TBXAS1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10926674 | 0.83 | CYP19A1 (0.43) | CYP19A1MAPTKDM4ETBXAS1CYP11B1 | |
| SCHEMBL10925433 | 0.82 | CYP11B1 (0.46) | CYP19A1MAPTTBXAS1CYP11B1CYP11B2 | |
| SCHEMBL10926775 | 0.82 | CYP19A1 (0.42) | CYP19A1MAPTKDM4ETBXAS1CYP11B1 | |
| SCHEMBL10927545 | 0.81 | CYP19A1 (0.47) | CYP19A1MAPTTBXAS1CYP11B1CYP11B2 | |
| SCHEMBL10929580 | 0.80 | TBXAS1 (0.35) | CYP19A1TBXAS1CYP11B1ALDH1A1MAPK1 | |
| SCHEMBL10922968 | 0.80 | CYP19A1 (0.40) | CYP19A1MAPTKDM4ETBXAS1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |