Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10929580 | 0.89 | TBXAS1 (0.35) | TBXAS1ALDH1A1SMN1; SMN2MAPK1GAA | |
| SCHEMBL10932093 | 0.88 | CYP17A1 (0.45) | TBXAS1MAPTALDH1A1KMT2AUSP2 | |
| SCHEMBL10928226 | 0.87 | CYP2D6 (0.41) | TBXAS1MAPTKDM4EESR2CYP3A4 | |
| SCHEMBL10922983 | 0.85 | CYP19A1 (0.43) | TBXAS1MAPTKDM4EESR2ALDH1A1 | |
| SCHEMBL10924986 | 0.84 | SMN1; SMN2 (0.37) | TBXAS1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL10925660 | 0.84 | CYP19A1 (0.41) | TBXAS1MAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10923896 | 0.83 | MAPT (0.36) | TBXAS1MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL10929266 | 0.83 | CYP3A4 (0.40) | TBXAS1MAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10928025 | 0.82 | TBXAS1 (0.51) | TBXAS1MAPTALDH1A1KMT2AHSD17B10 | |
| SCHEMBL10925022 | 0.82 | HMOX1 (0.43) | TBXAS1MAPTCYP3A4CYP1A2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4518607-A | FUNGICIDES, BACXTERICIDES AND ANTIPROTOZOA AGENTS | SYNTEX (U.S.A.) INC. (US) | 1985-05-21 | — | — | US | disclosed |