Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925320 | 0.91 | MEN1 (0.52) | ALDH1A1HTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL10929745 | 0.78 | MEN1 (0.53) | ALDH1A1HTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL11401365 | 0.75 | ALDH1A1 (0.63) | ALDH1A1HTTKMT2AMEN1KDM4E | |
| SCHEMBL10928162 | 0.74 | LMNA (0.66) | HTTKMT2AMEN1LMNACYP2C19 | |
| SCHEMBL10925916 | 0.74 | LMNA (0.57) | ALDH1A1HTTLMNACYP2C19GAA | |
| SCHEMBL24479794 | 0.73 | ALDH1A1 (0.61) | ALDH1A1HTTKMT2AMEN1KDM4E | |
| SCHEMBL28298203 | 0.73 | CHRM2 (0.79) | ALDH1A1HTTKMT2AMEN1TP53 | |
| SCHEMBL17100653 | 0.73 | MEN1 (0.59) | ALDH1A1HTTKMT2AMEN1L3MBTL1 | |
| SCHEMBL10927174 | 0.72 | MEN1 (0.59) | ALDH1A1HTTKMT2AMEN1KDM4E | |
| SCHEMBL27249206 | 0.72 | MEN1 (0.67) | ALDH1A1HTTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | claimed |
| EP-0189080-A2 | (1,2,4-Oxadiazol-3-YL)-arylmethanones, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-07-30 | — | — | EP | disclosed |
| US-4562186-A | HYPOTENSIVE, ANALGESICS, AND ANTIINFLAMMATORY AGENTS | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-12-31 | — | — | US | disclosed |