Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.48 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.48 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.48 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.48 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4765776 | 0.87 | ALDH1A1 (0.44) | PDE4BPDE4DMAPTALDH1A1PDE4A | |
| SCHEMBL10998352 | 0.86 | MAPT (0.54) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL4768036 | 0.82 | HPN (0.47) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL10924474 | 0.81 | HTT (0.44) | MAPTALDH1A1ADORA3SMN1; SMN2MEN1 | |
| SCHEMBL4289304 | 0.81 | MAPT (0.56) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL14221817 | 0.78 | MAPT (0.53) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL11776841 | 0.76 | PDE4B (0.54) | PDE4BPDE4DMAPTALDH1A1CACNA1F | |
| SCHEMBL11002375 | 0.76 | ALDH1A1 (0.56) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL28679065 | 0.75 | PDE4B (0.56) | PDE4BPDE4DMAPTALDH1A1CACNA1F | |
| SCHEMBL10999963 | 0.74 | CA12 (0.47) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177596-A1 | BETA-LACTAM DERIVATIVES, PREPARATION, COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1986-04-16 | — | — | EP | disclosed |
| WO-1985004878-A1 | BETA-LACTAM DERIVATIVES, PREPARATION, COMPOSITIONS CONTAINING THEM | BEECHAM GROUP P.L.C. (GB) | 1985-11-07 | — | — | WO | disclosed |