Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA7 | P43166 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002375 | 0.90 | ALDH1A1 (0.56) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL10964546 | 0.88 | LMNA (0.49) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL29691263 | 0.88 | NPSR1 (0.56) | CA12CA9ALDH1A1MEN1KMT2A | |
| SCHEMBL4289304 | 0.87 | MAPT (0.56) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL11004340 | 0.86 | ALDH1A1 (0.49) | CA12CA2CA7CA9CA14 | |
| SCHEMBL10998352 | 0.83 | MAPT (0.54) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL10924474 | 0.78 | HTT (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL20653919 | 0.74 | KMT2A (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10922925 | 0.73 | RAB9A (0.47) | ALDH1A1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL3201467 | 0.72 | KMT2A (0.49) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537886-A | β-lactam antibacterial agents and compositions containing them | BEECHAM GROUP P.L.C. (GB) | 1985-08-27 | — | — | US | disclosed |
| EP-0090656-A1 | Penicillins, a process for the preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1983-10-05 | — | — | EP | disclosed |