Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.53 |
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | JAK3 | P52333 | 1/20 | 0.53 |
| ▸ | PTGES | O14684 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10920620 | 0.81 | ALDH1A1 (0.49) | ALOX5SMN1; SMN2ADORA3HPGDSMAPK1 | |
| SCHEMBL2779302 | 0.78 | TDP1 (0.66) | ALOX5SMN1; SMN2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL10876349 | 0.77 | HSP90AA1 (0.54) | JAK2JAK3SMN1; SMN2MAPTL3MBTL1 | |
| SCHEMBL16110855 | 0.77 | KDM4E (0.61) | ALOX5JAK2JAK3PTGESTRPM8 | |
| SCHEMBL16110057 | 0.77 | KDM4E (0.61) | ALOX5JAK2JAK3PTGESTRPM8 | |
| SCHEMBL28478958 | 0.77 | TRPM8 (0.58) | ALOX5JAK2JAK3PTGESTRPM8 | |
| SCHEMBL10921204 | 0.77 | CA12 (0.42) | SMN1; SMN2ADORA3HPGDSMAPTALDH1A1 | |
| SCHEMBL10919855 | 0.76 | PDE4D (0.45) | SMN1; SMN2ADORA3HPGDSMAPTALDH1A1 | |
| SCHEMBL16699171 | 0.76 | ALPL (0.74) | JAK2JAK3TRPM8SMN1; SMN2HPGDS | |
| SCHEMBL30716607 | 0.76 | ALPL (0.74) | JAK2JAK3TRPM8SMN1; SMN2HPGDS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0177242-A2 | Pollen formation inhibiting pyrazoles | ELI LILLY AND COMPANY (US) | 1986-04-09 | — | — | EP | disclosed |