Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10631376 | 0.79 | CES1 (0.42) | MAPTRAB9AKMT2A | |
| SCHEMBL10631369 | 0.79 | CES1 (0.42) | MAPTRAB9AKMT2A | |
| SCHEMBL10718728 | 0.79 | CES1 (0.42) | MAPTRAB9AKMT2A | |
| SCHEMBL10508912 | 0.70 | CES2 (0.32) | — | |
| SCHEMBL10508908 | 0.70 | CES2 (0.32) | — | |
| SCHEMBL10843040 | 0.69 | HPGD (0.40) | RAB9A | |
| SCHEMBL9589970 | 0.69 | HPGD (0.40) | RAB9A | |
| SCHEMBL9589976 | 0.69 | HPGD (0.40) | RAB9A | |
| SCHEMBL9689334 | 0.67 | CRBN (0.37) | RAB9A | |
| SCHEMBL9689331 | 0.67 | CRBN (0.37) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0187085-A1 | 1-Substituted 6-fluoro-7-(pyrrol-1-yl)-1,4-dihydro-4-oxoquinoline-carboxylic-acid derivatives, their preparation and their use as medicaments | PROVESAN S.A. (CH) | 1986-07-09 | — | — | EP | disclosed |