Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.42 |
| ▸ | CES2 | O00748 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10718728 | 1.00 | CES1 (0.42) | CES1CES2NPC1RAB9AMEN1 | |
| SCHEMBL10631369 | 1.00 | CES1 (0.42) | CES1CES2NPC1RAB9AMEN1 | |
| SCHEMBL10628854 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL10628848 | 0.80 | ALDH1A1 (0.50) | MEN1KMT2ASMN1; SMN2CYP3A4KDM4E | |
| SCHEMBL10923994 | 0.79 | MAPT (0.33) | RAB9AKMT2AMAPT | |
| SCHEMBL9744912 | 0.77 | ALDH1A1 (0.47) | MEN1KMT2ASMN1; SMN2KDM4EMAPT | |
| SCHEMBL10508912 | 0.73 | CES2 (0.32) | CES1CES2 | |
| SCHEMBL10508908 | 0.73 | CES2 (0.32) | CES1CES2 | |
| SCHEMBL10843040 | 0.72 | HPGD (0.40) | NPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL9589970 | 0.72 | HPGD (0.40) | NPC1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4699992-A | 3-amino-2-benzoylacrylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | claimed |
| CN-113912539-B | Synthesis method of cyclopropanecarboxylic acid | 山东国邦药业有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113912539-A | Synthesis method of cyclopropanecarboxylic acid | 山东国邦药业有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-4762844-A | ANIMAL GROWTH REGULATORS | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |
| US-4699992-A | 3-amino-2-benzoylacrylic acid derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-10-13 | — | — | US | disclosed |
| CN-85101686-A | 3-amino-2-benzoyl-acrylic acid derivatives manufacture method | — | 1986-07-30 | — | — | CN | disclosed |