Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10554721 | 0.99 | NOX1 (0.48) | NOX1ALOX5L3MBTL1PARP10KDM4E | |
| SCHEMBL10919555 | 0.92 | ALOX5 (0.49) | NOX1ALOX5L3MBTL1PARP10KDM4E | |
| Bromide SCHEMBL10557453 | 0.91 | ALOX5 (0.48) | NOX1ALOX5L3MBTL1PARP10KDM4E | |
| SCHEMBL9375612 | 0.84 | NOX1 (0.59) | NOX1ALOX5L3MBTL1PARP10MAOB | |
| SCHEMBL10921930 | 0.84 | MEN1 (0.53) | L3MBTL1MEN1KMT2A | |
| SCHEMBL10923607 | 0.83 | L3MBTL1 (0.54) | NOX1ALOX5L3MBTL1PARP10MAOB | |
| Bromide SCHEMBL10552105 | 0.83 | MEN1 (0.51) | L3MBTL1MEN1KMT2A | |
| SCHEMBL10923141 | 0.82 | ALOX5 (0.53) | NOX1ALOX5L3MBTL1PARP10MAOB | |
| Bromide SCHEMBL10559873 | 0.82 | L3MBTL1 (0.53) | NOX1ALOX5L3MBTL1PARP10MAOB | |
| Bromide SCHEMBL10551551 | 0.81 | ALOX5 (0.52) | NOX1ALOX5L3MBTL1PARP10MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180994-A2 | Antihypertensive dialkyl aminoethylaniline derivatives | SYNTEX (U.S.A.) INC. (US) | 1986-05-14 | — | — | EP | disclosed |