Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SYK | P43405 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22362720 | 0.80 | MAPT (0.59) | PKMSYKMAPTKDM4EMEN1 | |
| SCHEMBL11647755 | 0.80 | KDM4E (0.47) | PKMMAPTKDM4EKMT2ARAB9A | |
| SCHEMBL12409072 | 0.76 | SYK (0.67) | PKMSYK | |
| SCHEMBL11652845 | 0.75 | RAB9A (0.46) | PKMSYKMAPTKDM4EMEN1 | |
| SCHEMBL22362704 | 0.75 | KMT2A (0.49) | PKMSYKMAPTKDM4EMEN1 | |
| SCHEMBL7981204 | 0.75 | CTNNB1 (0.60) | MAPTKDM4ECYP1A2KMT2ARAB9A | |
| SCHEMBL28408612 | 0.75 | RAB9A (0.71) | SYKMAPTKDM4EMEN1CYP1A2 | |
| SCHEMBL3283228 | 0.74 | RAB9A (0.57) | PKMSYKMAPTKDM4EMEN1 | |
| SCHEMBL2722644 | 0.73 | L3MBTL1 (0.65) | PKMMAPTKDM4ECYP2C19KMT2A | |
| SCHEMBL14781321 | 0.73 | SYK (0.54) | PKMSYKKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0091402-B1 | CHROMENOAZAINDOLIZINES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN PRESSURE OR HEAT SENSITIVE RECORDING MATERIALS | CIBA-GEIGY AG (CH) | 1986-02-26 | — | — | EP | disclosed |
| US-4506073-A | Chromenoazaindolizine compounds | CIBA-GEIGY CORPORATION (US) | 1985-03-19 | — | — | US | disclosed |
| EP-0091402-A2 | Chromenoazaindolizines, process for their preparation and their use in pressure or heat sensitive recording materials | CIBA-GEIGY AG (CH) | 1983-10-12 | — | — | EP | disclosed |