Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.60 |
| ▸ | WNT3A | P56704 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17985011 | 0.81 | KDM4E (0.60) | RAB9ANPC1KDM4EMAPTIDO1 | |
| SCHEMBL3452522 | 0.80 | RAB9A (0.62) | RAB9ANPC1KDM4EMAPTIDO1 | |
| SCHEMBL15942043 | 0.80 | RAB9A (0.54) | RAB9ANPC1KDM4EMAPTIDO1 | |
| Iodide SCHEMBL6263376 | 0.80 | KDM4E (0.59) | RAB9ANPC1KDM4EMAPTIDO1 | |
| SCHEMBL3452459 | 0.80 | RAB9A (0.62) | CTNNB1WNT3ARAB9ANPC1KDM4E | |
| SCHEMBL8804574 | 0.80 | RAB9A (0.50) | RAB9ANPC1KDM4EMAPTIDO1 | |
| SCHEMBL27332292 | 0.79 | NAPRT (0.54) | RAB9ANPC1KDM4EMAPTIDO1 | |
| SCHEMBL11618954 | 0.78 | RAB9A (0.49) | CTNNB1WNT3ARAB9ANPC1KDM4E | |
| SCHEMBL2722644 | 0.78 | L3MBTL1 (0.65) | RAB9ANPC1KDM4EMAPTIDO1 | |
| SCHEMBL11623530 | 0.78 | RAB9A (0.51) | RAB9ANPC1KDM4EMAPTIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6242612-B1 | Process for making substituted pyrazoles | G. D. SEARLE & CO. | 2001-06-05 | — | — | US | disclosed |