SCHEMBL1092940

SCHEMBL1092940

COCC(COC(C)=O)OC(C)=O

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.48
PRKCA P17252 4/20 0.45
AR P10275 1/20 0.43
GAA P10253 1/20 0.41
ALDH1A1 P00352 2/20 0.37
LMNA P02545 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triacetin SCHEMBL28108103 0.92 TDP1 (0.43) TDP1PRKCAARGAA
SCHEMBL11172217 0.91 TSHR (0.43) TDP1PRKCAALDH1A1LMNATSHR
Triacetin SCHEMBL3870 0.91 TDP1 (0.56) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL821340 0.91 TDP1 (0.56) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL8954226 0.89 TDP1 (0.50) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL1698261 0.89 TDP1 (0.50) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL3901859 0.89 PRKCA (0.50) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL8012678 0.89 TDP1 (0.54) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL16446056 0.89 TDP1 (0.54) TDP1PRKCAARGAAALDH1A1
Triacetin SCHEMBL16445622 0.89 TDP1 (0.54) TDP1PRKCAARGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230288610-A1 WAVELENGTH SELECTIVE ABSORPTION FILTER AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-09-14 US disclosed
WO-2022138082-A1 ACTIVE-ENERGY-CURABLE HARD COAT AGENT, HARD COAT LAYER, AND LAMINATE 東洋インキSCホールディングス株式会社 2022-06-30 WO disclosed
US-20200283464-A1 GLYCOSAMINOGLYCAN ESTER AND APPLICATION THEREOF CHENGDU AULI ECOLOGICAL TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2020-09-10 US disclosed
US-20180092915-A1 SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS PARION SCIENCES, INC. (US) 2018-04-05 US disclosed
US-9849129-B2 Sodium channel blockers for skin disorders PARION SCIENCES, INC. (US) 2017-12-26 US disclosed
WO-2016133967-A2 SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS PARION SCIENCES, INC. (US) 2016-08-25 WO disclosed
US-9354356-B2 Polymer film, and optically-compensatory film, polarizer and liquid-crystal display device comprising the same FUJIFILM CORPORATION (JP) 2016-05-31 US disclosed
US-20130253182-A1 POLYMER FILM, AND OPTICALLY-COMPENSATORY FILM, POLARIZER AND LIQUID-CRYSTAL DISPLAY DEVICE COMPRISING THE SAME NISHIURA TAKAKO (JP) 2013-09-26 US disclosed
US-8153731-B2 Comb (block) copolymers BYK=Chemie GmbH (DE) 2012-04-10 US disclosed
US-7858560-B2 Capture compounds, collections thereof and methods for analyzing the proteome and complex compositions CAPROTEC BIOANALYTICS GMBH (DE) 2010-12-28 US disclosed
US-20100099813-A1 Comb (block) copolymers BYK-CHEMIE GMBH (DE) 2010-04-22 US disclosed
US-7288119-B2 Leather treatment AUTOMOTIVE TECHNOLOGY, INC. (US) 2007-10-30 US disclosed
US-20060042018-A1 Quick-drying non-aqueous, thermoplastic leather dye of dye or pigment dispersed in polyacrylate resin, C-3 and C-4 alcohol mixture, n-butyl acetate, and propylene glycol monomethyl ether; dryable in less than one minute AUTOMOTIVE TECHNOLOGY, INC. 2006-03-02 US disclosed
US-7001435-B2 Method for dying leather with propylene glycol monomethyl ether (PGME) systems comprising adding polyacrylate resin base, C3 and C4 alcohols, and n-butyl acetate and negating the need for teflon dispersions, dibutyl phthalate, and improve AUTOMOTIVE TECHNOLOGY, INC. (US) 2006-02-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180092915-A1 SODIUM CHANNEL BLOCKERS FOR SKIN DISORDERS SCNN1B, SCNN1A, SCNN1G TDP1 2579/4885PRKCA 1361/4885AR 3225/4885
US-20200283464-A1 GLYCOSAMINOGLYCAN ESTER AND APPLICATION THEREOF LIPG, FABP4, ALPG TDP1 3734/4885PRKCA 2249/4885AR 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.